Los fosfolípidos de fosfatidilglicerol (PG) tienen una carga negativa debido a sus grupos fosfato polares cargados negativamente, lo que hace que toda la molécula se cargue negativamente. Dependiendo de las cadenas de ácidos grasos, los fosfolípidos PG comunes como dipalmitoilfosfatidilglicerol (DPPG) y dimiristoilfosfatidilglicerol (DMPG) muestran diferencias significativas en las temperaturas de transición de fase.
N. ° de registro NMPA CDE: F20180000838(A)
USFDA DMF No.: 032797
| Product Name | Dipalmitoyl Phosphatidylglycerole |
| Chemical Name | 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylglycerol (sodium salt) |
| CAS No. | 200880-41-7 |
| NMPA CDE registration no. | F20180000838 |
| USFDA DMF No. | 032797 |
| Quality grade | Injection |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C38H74O10PNa |
| Applications and examples | This product is Dipalmitoyl Phosphatidylglycerole (for injection), a fully synthetic phospholipid. It is suitable for the preparation of anionic liposomes and is a common choice of negatively charged membrane materials. It also plays a key role in improving the stability of liposomes. It has been widely used in the R&D of liposome drugs and the prescriptions of marketed products, and has also been used in some liposome projects in clinical stages, e.g., Lipoplatin. |
| Product code | S02003 |
| Package sizes | 1g, 10g |
| Storage condition | The product should be transported at -20 ± 5℃. It should be stored at -20℃ in well-closed containers, protected from light. Avoid exposure to strongly oxidizing media. It should be retested every 12 months when used and stored properly. |
Los fosfolípidos fosfatidilglicerol (PG) son ampliamente utilizados en la preparación de liposomas;
Las partículas lipídicas con cargas negativas pueden prevenir la agregación de partículas, mejorando así la estabilidad de las formulaciones;
Es más probable que las partículas de lípidos cargadas negativamente penetren en las membranas celulares para su administración.
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.
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